The 7 Best Tires for the Mercedes E350
Many people think that the Mercedes E350 is the complete car. It’s difficult to argue with them, given that this sedan has a super-luxurious interior, which you can make the most of thanks to its plush ride, powerful acceleration, and lots of passenger space.
However, all of the above qualities would amount to nothing if you pair your E350 with the wrong set of tires. That is because tires won’t just help this car carry you from point A to point B. In addition, they would either hurt or enhance its comfortable ride.
So, while the right set of tires may help put your fellow passengers to sleep. Cheap or inexpensive models may force you to question your decision-making skills. To prevent that from happening, we’ll provide you with the top seven best tires for the Mercedes E360.
#1. General Altimax RT43 – Best Overall

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Why is the General Altimax RT43 our top pick for the Mercedes E350?
Start with a comfortable year-round performance. This model’s dual-layer tread compound makes sure that its ride remains as plush under the sun as in rainy conditions. You can thus count on this tire to keep your E350’s ride noise- and vibration-free.
Next comes its ability to wear evenly. This means that the RT43 will provide consistent traction throughout its road life. Also, when a tire wears unevenly, its fuel consumption skyrockets, a problem you won’t be facing with this popular grand touring tire.
You may also appreciate that this model comes with a 75,000-mile treadwear warranty. As a driver for over two decades, I can assure you that such a guarantee means you can easily get 4 to 5 years out of the investment you’d be making in this model.
Which is great news once you look at its price tag. While the RT43 is by no means cheap, its asking price is 10-20% lower than what the likes of Michelin charge for their premium tires. This is huge since the difference in performance isn’t that much.
Pros
- Offers a quiet and comfortable ride
- Backed with a 75,000-mile treadwear warranty
- Asking price won’t blow a hole in your pocket
Cons
- – Steering feedback could be better
#2. Bridgestone Turanza QuietTrack – Best Grand Touring

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The Bridgestone Turanza QuietTrack rivals our top pick on various counts.
Like the Altimax RT43, this model eats smaller imperfections, helping you get the famed ride quality E350 is famous for. It is also insanely quiet – I can vouch for this grand touring tire making little to no noise at speeds below 80 miles per hour.
Its wet performance can also stand up to RT43’s. The Turanza QuietTrack has multiple grooves for quick and effective water evacuation and a reduced risk of hydroplaning. It also has the biting edges needed to safely carry you from point A to point B on snow.
Unlike the RT43, this model takes no prisoners on performance.
Whether you’re driving on dry or wet roads, the steering responsiveness and feedback will be top-notch. The same could be said with its high-speed stability, which is also brilliant. In fact, were it not for its relatively high asking price, this tire would have been our top pick.
Pros
- Offers dynamic handling and performance
- Backed with an 80,000-mile treadwear warranty
- One of the quietest tires on the market
Cons
- Asking price may prove to be a deal breaker
#3. Pirelli Cinturato P7 All Season Plus II – Best All-Season

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The Pirelli Cinturato P7 checks several boxes for E350 drivers.
A high-silica tread compound enables this tire to offer supreme wet traction, distinguishing this tire from rival all-season touring tires. Plus, since the rubber is molded into an asymmetric tread pattern, better traction on dry and snow surfaces is also guaranteed.
Having used this model’s predecessor, I always believed any upcoming tire would struggle to match its fuel efficiency. Fortunately, the P7 All-Season Plus II has proved me wrong. Thanks to its 5% larger contact area, this model consumes even less fuel than its precursor.
Tread life is one area where this tire hasn’t improved over its predecessor. But that isn’t something that should prove to be a deal-breaker. Both tires come with a 70,000-mile mileage warranty, which should translate into 4 to 5 years of road life if you drive conservatively.
Pros
- Exceptional wet traction and handling
- Delivers a quiet and comfortable ride
- Offers decent steering feedback
Cons
- Snow performance could be better
#4. Bridgestone Potenza RE980 AS – Best All-Season

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Just as many people think that the Mercedes E350 is a complete car, so are there are drivers thinking performance tires cannot get any better than the Potenza RE980AS.
Having seen this tire’s performance from the passenger seat, I agree with the above sentiment. The RE980 AS is one of those tires that justify the word ‘exceptional’ when it’s used to describe their cornering grip. Its straight-line tracking and high-speed stability are equally great.
Thanks to its asymmetric tread pattern, this model also delivers a sure-footed driving experience on wet and dry roads. Plus, the sight of multiple circumferential grooves in its tread area should convince you that it won’t skid or slip over wet or light snowy surfaces.
Steering feedback is another area where this model shines. Its continuous center rib and multiple shoulder blocks ensure you get the maximum feel of what is going down there on the road. Small wonder, then, that this model has the annoying ‘ability’ to wear unevenly.
Pros
- Extremely short braking distances
- Top-notch responsiveness and dry handling
- Excellent wet traction for an ultra-high-performance tire
Cons
- May wear unevenly if pushed to its limits
#5. Goodyear Assurance WeatherReady – Best All-Weather

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The Goodyear Assurance WeatherReady is one of my favorite all-weather tires. It can become yours too, provided you pair it with your ES350. Here’s why I’m so confident.
This model delivers outstanding traction on dry and wet roads, with a steering feedback you rarely expect from tires in this category. Plus, thanks to its optimized symmetric tread pattern, it will enhance not hurt your E350’s already plush ride quality.
It will also impress you with its wet performance. Goodyear has equipped this model with its proprietary traction grooves to help it tackle the worst of weather conditions. As such, you won’t have to take your foot off the accelerator in the rain.
You can also count on this model to provide consistent traction throughout its road life, something not many tires are capable of offering. Another thing you can rely on this model to do is offer excellent performance in mild wintry conditions.
Unfortunately, there is one area where the WeatherReady could do better. Its 60,000-mile treadwear warranty is at least 10,000 miles shorter than average.
Pros
- Offers exceptional traction on snow
- Delivers great steering feedback for an all-weather tire
- Keeps the ride quiet and comfortable
Cons
- Relatively small treadwear warranty
#6. Goodyear Eagle F1 Asymmetric 3 ROF – Best Run-Flat

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Some Mercedes E350 trims come with run-flat tires from the factory. If that’s the case with the trim you’re driving, consider the Eagle F1 Asymmetric 3 ROF.
Goodyear has reinforced this model’s walls vis-à-vis its ‘standard’ colleague. It has also provided it with a relatively tougher tread compound. The result? The Eagle F1 Asymmetric 3 can be safely driven at speeds of up to 50 mph per for up to 50 miles with zero air pressure.
Given that it’s a high-performance tire, excellent cornering performance is a given. This model also boasts short braking distances, a boon on dry roads. Plus, unlike the majority of run flat tires, the F1 Asymmetric 3 ROF doesn’t growl at high speeds, even when fully flat.
That isn’t to say that this model is faultless. Its wet traction is sub-par when compared with standard performance or high-performance tires. However, to compensate for this shortcoming, this model delivers outstanding responsiveness, even for an ROF tire.
All in all, if you could make do with average wet traction in return for excellent steering feedback and the knowledge that this model won’t leave you stranded in the middle of nowhere (as it can be run flat), go for the Eagle F1 Asymmetric 3.
Pros
- Can be run flat for up to 50 miles at speeds below 50 mph
- Offers excellent steering feedback and high-speed stability
- Relatively quiet for a max-performance tire
Cons
- Wet traction could be better
#7. Michelin X-Ice XI3 – Best Winter Tires

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The Michelin X-Ice Xi3 has what it takes to safely carry your E350 from point A to point B in harsh wintry conditions. Aside from that, it comes with a 40,000-mile treadwear warranty, a rarity for any winter tire (just ask Bridgestone, whose flagship winter tire comes with no tread guarantee).
Michelin’s Flex-Ice tread compound sees to it that this tire’s rubber stays flexible in sub-zero temperatures. This, in turn, gives the XI3 the power to dig through sheets of snow and ice and grip the hard surface underneath. The result is excellent and consistent traction.
Cross-Z sipes do what the tread compound fails to – they help the XI3 plow through snow and ice. This tire also features multiple circumferential grooves to help with water evacuation. As such, the risk of hydroplaning or skidding on slipping on wet/winter roads is minimal.
Lastly, there are two areas where this model sets itself apart from premium winter tires. The first of which is the above treadwear warranty (most winter tires receive zero backing from their manufacturers). The second, meanwhile, is its ability to consume less gas than competition.
Pros
- Offers exceptional snow and ice traction
- Backed with a 40,000-mile treadwear warranty
- Very short braking distances in inclement weather
Cons
- Pricey, even for a premium winter tire
Best Tires for the Mercedes E350
All-Season Touring and Grand Touring
All-season tires provide E350 owners with the best of both worlds. On the one end, these tires deliver exceptional ride quality, fuel economy, and road manners. They have the ability to glide over minor imperfections without letting you know about them.
On the other end, the best all-season tires cost less than the likes of high-performance and ultra-high-performance tires. Throw their substantial treadwear warranties into the mix (our 2nd pick is backed to last 80,000 miles), and these tires offer a decent return on investment.
High-Performance and Ultra-High-Performance
Despite all the qualities of all-season tires, many E350 drivers opt for performance or high-performance radials. Here’s why that is the case.
Whether your E350 is powered by the turbocharged I-4 engine or it comes with the silky smooth I-6, only performance or high-performance tires can make the most of power on offer. That too while offering stunning steering feedback, cornering performance, and grip.
Bear in mind, though, that these tires don’t care much about your pocket. Unlike their all-season counterparts, HP and UHP tires are fuel guzzlers. They also wear unevenly if pushed to the limits, meaning you can’t take their elevated asking prices as proofs of long road life.
Winter Tires
If you deal with snow, ice and slush regularly, winter tires are a no-brainer.
As the X-Ice XI3 has shown, these tires come with a specialized tread compound designed for sub-zero temperatures. Unlike other types of tires, these models’ rubber doesn’t get stiff on encountering snow, a critical requirement if you want to drive safely in harsh wintry conditions.
Conclusion
Nobody can deny that the Mercedes E350 is one of the best luxury sedans on the market. Yet the importance of pairing this car with the right set of tires cannot be ignored, especially if you want to make the most of its ride-related qualities. It’s thus suggested to pair the E350 with premium tires.